Research in the Zhou Lab focuses on elucidating mechanisms regulating tissue homeostasis and inflammation. Mammalian tissues are ecological communities of diverse cell types, including immune cells, stromal cells, neurons, endothelial cells, and tissue parenchymal cells. It's becoming clear that immune cells are integral members of the tissue ecosystem. We are interested in studying how immune cells communicate with their tissue neighbors and surrounding environment to maintain homeostatic states of tissues, and how dysregulation of cell-cell and cell-environment interactions may lead to inflammatory disorders.
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